Email updates

Keep up to date with the latest news and content from Cardiovascular Ultrasound and BioMed Central.

Open Access Highly Accessed Open Badges Research

Incidence of post myocardial infarction left ventricular thrombus formation in the era of primary percutaneous intervention and glycoprotein IIb/IIIa inhibitors. A prospective observational study

Arshad Rehan1, Manpreet Kanwar1, Howard Rosman1*, Sujood Ahmed1, Arshad Ali2, Julius Gardin1 and Gerald Cohen1

Author Affiliations

1 Department of Cardiology, St John Hospital and Medical Centre, Wayne State University, 22101 Moross Road, Detroit, Michigan 48230, USA

2 Department of Cardiology, Guthrie Clinic Sayre, Guthrie Square, Sayer, Pennsylvania 18840, USA

For all author emails, please log on.

Cardiovascular Ultrasound 2006, 4:20  doi:10.1186/1476-7120-4-20

Published: 6 April 2006



Before the widespread use of primary percutaneous coronary intervention (PCI) and glycoprotein IIb/IIIa inhibitors (GP IIb/IIIa) left ventricular (LV) thrombus formation had been reported to complicate up to 20% of acute myocardial infarctions (AMI). The incidence of LV thrombus formation with these treatment modalities is not well known.


92 consecutive patients with ST-elevation AMI treated with PCI and GP IIb/IIIa inhibitors underwent 2-D echocardiograms, with and without echo contrast agent, within 24–72 hours.


Only 4/92 (4.3%) had an LV thrombus, representing a significantly lower incidence than that reported in the pre-PCI era. Use of contrast agents did not improve detection of LV thrombi in our study.


The incidence of LV thrombus formation after acute MI, in the current era of rapid reperfusion, is lower than what has been historically reported.