Research

Assessment of left ventricular volumes using simplified 3-D echocardiography and computed tomography – a phantom and clinical study

Mattias Mårtensson¹ , Reidar Winter² , Kerstin Cederlund³ , Jonaz Ripsweden³ , Habib Mir-Akbari⁴ , Jacek Nowak² and Lars-Åke Brodin¹

¹  School for Technology and Health, Royal Institute of Technology, Flemingsberg, Stockholm, Sweden

²  Department of Clinical Physiology, Karolinska University Hospital in Huddinge, Stockholm, Sweden

³  Department of Radiology, Karolinska Institutet, Stockholm, Sweden

⁴  Department of Cardiology, Karolinska University Hospital in Huddinge, Stockholm, Sweden

author email corresponding author email

Cardiovascular Ultrasound 2008, 6:26doi:10.1186/1476-7120-6-26

Published:	4 June 2008

Abstract

Objectives

To compare the accuracy of simplified 3-dimensional (3-D) echocardiography vs. multi-slice computed tomography (MSCT) software for the quantification of left ventricular (LV) volumes.

Design

Three-D echocardiography (3-planes approach) and MSCT-CardIQ software were calibrated by measuring known volumes of 10 phantoms designed to closely mimic blood-endocardium interface. Subsequently, LV volumes were measured with both the methods in 9 patients referred routinely for coronary angiography and the agreement between the measurements was evaluated.

Results

Simplified 3D-echocardiography provided higher degree of agreement between the measured and true phantom volumes (mean difference 0 ± 1 ml, variation range +4 to -4 ml) than MSCT software (mean difference 6 ± 5 ml; variation range +22 to -10 ml). The agreement between LV measurements in the patients was considerably poorer, with significantly larger volumes produced by MSCT (mean difference -23 ± 40 ml, variation between +93 and -138 ml).

Conclusion

Simplified 3-D echocardiography provides more accurate assessment of phantom volumes than MSCT-CardIQ software. The discrepancy between the results of LV measurements with the two methods is even greater and does not warrant their interchangeable diagnostic use.