|
Characteristics of all participants and of subsets with and without carotid lesions at baseline, Atherosclerosis Risk in Communities Limited Access Data, 1987–89. |
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| Full Study |
Carotid Lesions: |
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| Sample |
Present |
Absent |
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| N = 7956 |
N = 2955 |
N = 5001 |
p-value |
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|
|
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| Age, years (mean (SD)) |
54.0 (5.7) |
55.7 (5.5) |
53.0 (5.6) |
<0.0001 |
|
| Male Gender (%) |
43.4 |
52 |
38.3 |
<0.0001 |
|
| Black race (%) |
22.6 |
21.1 |
23.4 |
0.02 |
|
| Smoker (%) |
Current |
25.6 |
31.7 |
21.9 |
<0.0001 |
| Former |
31.4 |
34.2 |
29.8 |
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| Never |
43.0 |
34.2 |
48.3 |
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| Cigarette years* (mean (SD)) |
660 (418) |
735 (449) |
596 (379) |
<0.0001 |
|
| Drinker (%) |
Current |
58.5 |
58.6 |
58.4 |
0.0002 |
| Former |
17.3 |
19.3 |
16.1 |
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| Never |
24.2 |
22.0 |
25.4 |
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| Ethanol, grams/week† (mean (SD)) |
72 (111) |
79 (125) |
60 (102) |
<0.0001 |
|
| Diabetes (%) |
8.8 |
10.3 |
7.9 |
0.0002 |
|
| Hypertension medication (%) |
24.6 |
36.5 |
26.8 |
<0.0001 |
|
| Cholesterol medication (%) |
2.8 |
3.4 |
2.4 |
0.011 |
|
| Body Mass Index (mean (SD)) |
26.7 (4.6) |
26.5 (4.4) |
26.8 (4.7) |
0.0032 |
|
| Systolic BP, mm Hg (mean (SD)) |
120 (18) |
123 (19) |
118 (17) |
<0.0001 |
|
| Diastolic BP, mm Hg (mean (SD)) |
72.7 (10.9) |
73.0 (11.0) |
72.6 (10.9) |
0.146 |
|
| LDL-C, mmol/L (mean (SD)) |
3.53 (1.00) |
3.69 (0.98) |
3.44 (1.01) |
<0.0001 |
|
| HDL-C, mmol/L (mean (SD)) |
1.38 (0.45) |
1.32 (0.43) |
1.41 (0.46) |
<0.0001 |
|
| Fibrinogen, mg/dL (mean (SD)) |
298 (63) |
305 (64) |
294 (62) |
<0.0001 |
|
| White blood count, 1000s/μL (mean (SD)) |
6.0 (1.9) |
6.3 (2.0) |
5.9 (1.8) |
<0.0001 |
|
| Blood glucose, mg/dL (mean (SD)) |
105 (33) |
107 (36) |
104 (31) |
<0.0001 |
|
| Sport index (mean (SD)) |
2.47 (0.80) |
2.48 (0.79) |
2.47 (0.81) |
0.34 |
|
| Standing height, cm (mean (SE)) ‡ |
168.5 (0.1) |
169 (0.11) |
169.6 (0.09) |
<0.0001 |
|
| RCCA measures (mean (SE)) § |
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| Intima-medial thickness (mm) |
0.65 (0.002) |
0.71 (0.003) |
0.63 (0.002) |
<0.0001 |
|
| Diameter (mm) |
7.72 (0.01) |
7.94 (0.01) |
7.65 (0.01) |
<0.0001 |
|
| Circular wall area (mm2) |
14.6 (0.05) |
16.2 (0.08) |
13.9 (0.06) |
<0.0001 |
|
| Elliptical wall area (mm2) |
20.9 (0.06) |
22.8 (0.09) |
20.1 (0.07) |
<0.0001 |
|
|
BP = blood pressure. IMT = intima-media thickness. RCCA = right common carotid artery. SD = standard deviation. SE = standard error. N = Maximum number possible. Lower numbers were available for some variables because of missing information. * Among current smokers. †Among current drinkers. ‡Height is adjusted for gender in the carotid lesion subsets. § RCCA measures are adjusted for height and gender in the carotid lesion subsets. | |||||
Eigenbrodt et al. Cardiovascular Ultrasound 2008 6:10 doi:10.1186/1476-7120-6-10 |
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