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TCD and cerebral blood flow modifications. MCA: middle cerebral artery. CPB: cardiopulmonary bypass. CBF: cerebral blood flow. |
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| Author [reference] |
Journal (Year of Publication) |
Type of study and Number of patients |
Main findings |
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| Lindegaard KF [4] |
Stroke (1987) |
Observational on 7 adult patients |
Linear relationship between flow volume and blood velocity in MCA is present. |
| Weyland A [5] |
Anesthesiology (1994) |
Observational on 15 adult patients |
Linear relationship between flow volume and blood velocity in MCA is present before and after CPB but cannot reliably predict percentage changes in CBF during CPB. |
| Bishop CCR [6] |
Stroke (1986) |
Observational on 17 adult patients |
Changes in MCA velocity reliably correlate with changes with CBF evaluated with Xenon133 |
| Rosemberg A [7] |
Pediatric Research (1985) |
Experimental in newborn lambs |
Changes in cerebral blood flow velocity are useful qualitative measures of changes in cerebral blood flow |
| Trivedi U [8] |
Annals of Thoracic Surgery (1997) |
Randomized trial on 60 adult patients receiving either α-stat or pH stat management based CPB |
Measurement of MCA velocity by TCD expressed as relative changes of a pre-CPB level can be used to examine CBF changes during CPB |
Polito et al. Cardiovascular Ultrasound 2006 4:47 doi:10.1186/1476-7120-4-47 |
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