Cerebral blood flow during cardiopulmonary bypass in pediatric cardiac surgery: the role of transcranial Doppler – a systematic review of the literature

doi:10.1186/1476-7120-4-47

Cardiovascular Ultrasound

Volume 4

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Polito A
Ricci Z
Di Chiara L
Giorni C
Iacoella C
Sanders SP
Picardo S

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Ricci Z
Di Chiara L
Giorni C
Iacoella C
Sanders SP
Picardo S
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Review

Cerebral blood flow during cardiopulmonary bypass in pediatric cardiac surgery: the role of transcranial Doppler – a systematic review of the literature

Angelo Polito , Zaccaria Ricci , Luca Di Chiara , Chiara Giorni , Claudia Iacoella , Stephen P Sanders and Sergio Picardo

Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Hospital, Rome, Italy

author email corresponding author email

Cardiovascular Ultrasound 2006, 4:47doi:10.1186/1476-7120-4-47


Published:	13 December 2006

Abstract

Background

Transcranial Doppler Ultrasound (TCD) is a sensitive, real time tool for monitoring cerebral blood flow velocity (CBFV). This technique is fast, accurate, reproducible and noninvasive. In the setting of congenital heart surgery, TCD finds application in the evaluation of cerebral blood flow variations during cardiopulmonary bypass (CPB).

Methodology

We performed a search on human studies published on the MEDLINE using the keyword "trans cranial Doppler" crossed with "pediatric cardiac surgery" AND "cardio pulmonary by pass", OR deep hypothermic cardiac arrest", OR "neurological monitoring".

Discussion

Current scientific evidence suggests a good correlation between changes in cbral blood flow and mean cerebral artery (MCA) blood flow velocity. The introduction of Doppler technology has allowed an accurate monitorization of cerebral blood flow (CBF) during circulatory arrest and low-flow CPB. TCD has also been utilized in detecting cerebral emboli, improper cannulation or cross clamping of aortic arch vessels. Limitations of TCD routine utilization are represented by the need of a learning curve and some experience by the operators, as well as the need of implementing CBF informations with, for example, data on brain tissue oxygen delivery and consumption.

Conclusion

In this light, TCD plays an essential role in multimodal neurological monitorization during CPB (Near Infrared Spectroscopy, TCD, processed electro encephalography) that, according to recent studies, can help to significantly improve neurological outcome after cardiac surgery in neonates and pediatric patients.