|
Coronary blood flow and vessel diameter. |
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| All patients |
CP positive |
p |
CP negative |
|
|
|
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| CBF (ml / min) (+/- percentchange) |
||||
| baseline |
22.6 ± 14.39 |
22.0 ± 13.80 |
→ 0.503 ← |
23.4 ± 15.28 |
| ACh D1 |
39.6 ± 21.21 (+75.2%) |
40.4 ± 22.34 (+83.6%) |
→ 0.172 ← |
38.5 ± 19.33 (+64.5%) |
| ACh D2 |
48.7 ± 30.34 (+115.5%) |
51.6 ± 27.82 (+134.5%) |
→ 0.177 ← |
41.3 ± 34.78 (+76.5%) |
| NaCl (control) |
23.1 ± 12.15 (+2.2%) |
22.1 ± 12.38 (+0.4%) |
→ 0.697 ← |
24.7 ± 11.57 (+5.5%) |
| NTG |
40.3 ± 23.06 (+78.3%) |
39.5 ± 20.74 (+79.5%) |
→ 0.696 ← |
41.0 ± 24.74 (+75.2%) |
| Vessel diameter (mm) (+/- percent change) |
||||
| baseline |
2.53 ± 0.50 |
2.55 ± 0.50 |
→ 0.773 ← |
2.51 ± 0.48 |
| ACh D1 |
2.55 ± 0.50 (+0.8%) |
2.56 ± 0.52 (+0.4%) |
→ 0.658 ← |
2.54 ± 0.46 (+1.2%) |
| ACh D2 |
2.54 ± 0.61 (+0.3%) |
2.60 ± 0.62 (+2.0%) |
→ 0.289 ← |
2.46 ± 0.58 (-2.0%) |
| NaCl (control) |
2.54 ± 0.45 (+0.1%) |
2.52 ± 0.48 (-1.1%) |
→ 0.543 ← |
2.58 ± 0.39 (+2.7%) |
| NTG |
2.88 ± 0.52 (+13.8%) |
2.88 ± 0.47 (+13.0%) |
→ 0.801 ← |
2.89 ± 0.60 (+15.1%) |
| CFVR |
3.0 ± 0.27 |
3.1 ± 0.31 |
→ 0.652 ← |
3.0 ± 0.10 |
|
Coronary blood flow (CBF) and vessel diameter before (baseline) and after i. c. infusion of acetylcholine (ACh) at medium dose (ACh D1: 7.2 μg/min → 1/2 × 10-6 mol/l) and high dose (ACh D2: 36 μg/min → 1/4 × 10-5 mol/l), 0.2 mg nitroglycerin (NTG), continuous infusion of saline (NaCl 0.9 % at 2 ml/min) served as control. The comparison of the CBF, and of the vessel diameter with the corresponding baseline value is expressed as percent change. CFVR: coronary flow velocity reserve (adenosine i. c. versus baseline), CP: Chlamydia pneumoniae. {values are mean ± SD, p values of two-tailed student's t-test} | ||||
Ferrari et al. Cardiovascular Ultrasound 2005 3:12 doi:10.1186/1476-7120-3-12 |
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