Table 1

Comparison of echocardiography and MRI findings between Anderson-Fabry and hypertrophic cardiomyopathy.

Echocardiography


Anderson-Fabry
HCM

LVH pattern
Concentric>Asymmetric
Asymmetric>Concentric

Resting LVOT gradient
Rare
25–30%

Massive LVH> 30 mm
Rare
10–15%

LV diastolic dysfunction (tissue Doppler, strain rate)


          With LVH
Yes
Yes
          Without LVH (genotype +)
Yes
Yes

LV systolic dysfunction
More frequent especially in older males


Magnetic resonance

Most common site of late-enhancement (if present)
Infero-lateral segment
Ventricular junction, Multi-focal

LVH- left ventricular hypertrophy; LVOT – left ventricular outflow tract

Dimitrow et al. Cardiovascular Ultrasound 2005 3:11   doi:10.1186/1476-7120-3-11